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Molecular Biology Reagents for Life Science Research

Exreprotein LLC is a leading U.S. supplier of molecular biology reagents, delivering high-performance tools that support both routine and advanced workflows in academic, biotechnology, and pharmaceutical laboratories. Our comprehensive portfolio includes RNA extraction kits, DNA extraction kits, DNA extraction and purification kits, genomic DNA extraction kits, and specialized enzymes such as SUMO protease, restriction endonuclease enzymes, and EXRENuclease (Benzonase®-like nuclease).

All products are optimized for reproducibility, purity, and ease of use, ensuring consistent experimental outcomes. Reagents are supplied for research use only (RUO).

Our key molecular biology reagents include:

  • DNA extraction kit solutions for cells and tissues
  • RNA extraction kit systems for total RNA isolation
  • DNA extraction and purification kit formats for high-purity recovery
  • Genomic DNA extraction kit products for large-fragment DNA isolation
  • Restriction endonuclease enzyme systems for precise DNA digestion
  • SUMO protease for fusion tag removal
  • EXRENuclease for nucleic acid degradation during bioprocessing
  • Buffers, columns, and enzyme systems for downstream processing

These reagents support applications such as cloning, sequencing, PCR/qPCR, gene expression analysis, protein expression, and functional genomics.

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EXact-Cut™ MspI Restriction Endonuclease
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EXact-Cut™ NcoI Restriction Endonuclease
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EXact-Cut™ NdeI Restriction Endonuclease
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EXact-Cut™ NheI Restriction Endonuclease
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EXact-Cut™ NotI Restriction Endonuclease
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EXact-Cut™ NruI Restriction Endonuclease
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EXact-Cut™ NsiI Restriction Endonuclease
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EXact-Cut™ PacI Restriction Endonuclease
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EXact-Cut™ PmeI Restriction Endonuclease
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EXact-Cut™ PspGI (EcoRII) Restriction Endonuclease

Restriction Endonuclease Enzyme Systems

Our restriction endonuclease enzymes enable accurate DNA cutting at defined recognition sequences, supporting precise genetic manipulation.

Used for:

  • Molecular cloning
  • Vector construction
  • DNA mapping
  • Synthetic biology
  • Gene editing preparation

Each enzyme is supplied with optimized buffers to ensure consistent digestion efficiency and reproducibility.

DNA & RNA Extraction Kits for Cells and Tissue Samples

High-quality nucleic acid isolation is the foundation of every successful molecular biology experiment. Exreprotein LLC provides optimized DNA and RNA extraction kits designed for efficient lysis, purification, and recovery from diverse biological materials.

DNA & RNA Extraction Solutions

Our DNA extraction kits and RNA extraction kits are validated for:

  • Mammalian cultured cells
  • Bacterial and yeast samples
  • Fresh or frozen tissues
  • Microbial and environmental samples
  • Purification of PCR product

Key benefits

  • Efficient lysis and strong nucleic acid binding
  • Removal of proteins, lipids, and inhibitors
  • High yield and purity
  • Fast, streamlined protocols
  • Compatibility with PCR, qPCR, cloning, and sequencing

Enzymes for Molecular Biology and Protein Workflows

In addition to extraction kits, Exreprotein LLC supplies high-quality enzymes critical for DNA/RNA and protein research.

SUMO Protease for Fusion Tag Removal

SUMO protease is widely used in recombinant protein workflows for precise removal of SUMO fusion tags.

Features:

  • Highly specific cleavage at the SUMO recognition site
  • Minimal off-target proteolysis
  • Preserves protein activity and structure
  • Ideal for native protein purification

This enzyme is essential for protein expression and purification pipelines that require clean tag removal.

EXRENuclease (Benzonase®-like Nuclease)

EXRENuclease degrades DNA and RNA into short oligonucleotides, improving lysate handling and purification performance.

Advantages:

  • Broad activity against ssDNA, dsDNA, and RNA
  • Reduces viscosity in cell lysates
  • Improves protein purification yields
  • Maintains protein integrity

Common uses:

  • Recombinant protein purification
  • Nucleic acid removal
  • Sample preparation for biochemical assays
  • Bioprocessing workflows

Benzonase® is a registered trademark of Merck KGaA, Darmstadt, Germany.

Quality and Performance You Can Trust

Exreprotein LLC molecular biology reagents are developed with strict quality controls to ensure dependable laboratory results.

Our standards include:

Purity & Activity Testing
Validated enzyme activity and nucleic acid recovery performance

Reproducibility
Lot-to-lot consistency to minimize variability

Compatibility
Seamless integration with PCR, cloning, sequencing, and protein workflows

Documentation & Traceability
Comprehensive technical datasheets and batch information