Human IL-6 Precoated ELISA Kit
$499.00
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In-stock products will arrive in 1 to 2 business days.
For Research Use Only.
Not Intended for Diagnostic or Therapeutic Use.
Key Features
✓ Assay Range: 3.13-200 pg/mL
✓ Sensitivity: 2 pg/mL
✓ Sample Types: Serum, Plasma, Cell Culture Supernates
Size
✓ 1 Kit (96 well plate)
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Product Details
Storage & Preparation
Data Images
Background
Product Documents
Product Details
| Product Type | Quantitative ELISA, Colorimetric |
| Product Summary |
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| Reactivity | Human IL-6
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| Product Components |
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Storage & Preparation
| Shipping | Shipped on blue ice |
| Stability & Storage | Store the unopened kit at 2-8℃, The kit is stable for 12 months. Do not use beyond expiration date. |
| Reconstitution | See Datasheet for Component Preparation |
Data Images
Human IL-6 ELISA standard curve, typical data. User-generated standard curve is required for each set of samples. Please refer to protocol.
Background
| Alternative Names | Interleukin 6, Interferon Beta-2, IFN-Beta-2, IFNB2, B-Cell Stimulatory Factor 2, BSF2, Hybridoma Growth Factor, HGF, HSF, CTL Differentiation Factor, CDF |
| Function | IL-6 plays a role in regulating immune response, inflammation, hematopoiesis, metabolism, and neurological processes. IL-6 influences the growth and differentiation of hematopoietic progenitor and stem cells. In the innate immune response, IL-6 is released by macrophages and dendritic cells. During the adaptive immune response, IL-6 plays a role in B cell maturation and differentiation of T cells into T follicular helper (Tfh) cells and Th17 cells. Muscle tissue and the central nervous system response to IL-6 has been linked to lipolysis and modulation of insulin response. IL-6 signaling occurs via binding to IL-6R alpha (CD126) and subsequent dimerization with the signal-transducing gp130 subunit. |
| Tissue Specificity | IL-6 expression has been reported in muscle tissue, endothelial tissue, lung, intestine, and adipose tissue. |
| Cellular Localization | Secreted protein |
| Involvement in Disease | Dysregulation of IL-6 is implicated in rheumatoid arthritis, systemic juvenile idiopathic arthritis (sJIA) inflammatory bowel disease (IBD), autoimmune hepatitis, atherosclerosis, insulin resistance, type 2 diabetes, fatty liver disease, obesity-related inflammation, Castleman disease, Behçet’s disease Alzheimer’s disease, systemic lupus erythematosus, multiple myeloma, and various cancers (prostate, breast, and lung) through actions on the tumor microenvironment. |
| UniProt | P05231 |
| Gene Symbol | IL6 |
| Entrez Gene ID | 3569 |
Product Documents
| Product Datasheet | Download Product Datasheet |
| COA | Contact Us |
| SDS | Contact Us |
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