Mouse IL-4 Precoated ELISpot Kit
$499.00
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Key Features
✓ Ready-to-use kit
✓ Detect analyte-secreting cells
Size
✓ 1 Kit (96 well plate)
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Product Details
Storage & Preparation
Data Images
Background
Product Documents
Product Details
Product Type | ELISpot Kit |
Reactivity | Mouse IL-4 |
Product Components |
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Storage & Preparation
Shipping | Shipped on blue ice |
Stability & Storage | Store the unopened kit at 2-8℃, The kit is stable for 12 months. Do not use beyond expiration date. |
Reconstitution | See Datasheet for Component Preparation |
Data Images
Background
Alternative Names | Interleukin 4, Lymphocyte Stimulatory Factor 1, B-Cell Stimulatory Factor 1, B Cell Growth Factor 1, BCGF1, BSF1, Binetrakin, Pitrakinra, MGC79402, IL4e12, IgG1 Induction Factor |
Function | Interleukin-4 (IL-4) is a cytokine involved in the regulation of immune and inflammatory responses. It promotes the differentiation of naïve T cells into Th2 cells, which in turn stimulate B cells to upregulate IgE antibodies. IL-4 is produced by mast cells, eosinophils, basophils and committed Th2 cells. There are two cell-dependent receptor complexes, either a heterodimer of IL-4 R alpha (CD124) and the common gamma chain (CD132) associated with hematopoietic cells or a heterodimer of IL-4 R alpha and IL-13 R alpha 1 (CD213A1) associated with non-hematopoietic cells. |
Tissue Specificity | IL-4 expression has been identified in lymph node and placenta. |
Cellular Localization | Secreted protein |
Involvement in Disease | Allergic inflammation, allergic rhinitis, asthma, atopic dermatitis, autoimmune disorders (rheumatoid arthritis, systemic lupus erythematosus (SLE), and multiple sclerosis), inflammatory bowel disease (IBD) and graft-versus-host disease (GVHD). |
UniProt | P07750 |
Gene Symbol | IL4 |
Entrez Gene ID | 16189 |
Product Documents
Product Datasheet | Download Product Datasheet |
COA | Contact Us |
SDS | Contact Us |
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